This course introduces novice end-users and artists to the basics of the OpenVDB data structure and its Houdini integration, and gives developers a more in-depth description of the accompanying toolset, class structures, and various optimization techniques. Since the previous SIGGRAPH course on OpenVDB (2015), the library has changed and expanded significantly. It includes many new tools and algorithms (new multi-resolutions tools, diverged-removal, diagnostic tools, etc) and new data structures (for example, significant improvements to better support particles and point attributes). This year, for the first time, the course includes material on ongoing work that ports the VDB data structure and some tools to the GPU.